Introduction
The STAX-12A All-in-One Molecular Diagnosis System is an open-reagent-platform instrument for trained professionals in laboratory settings. It integrates magnetic bead-based nucleic acid extraction and purification, automated liquid handling, PCR reaction preparation, real-time PCR amplification, fluorescence detection, and data analysis in one benchtop system.
Designed to process 1–12 samples simultaneously, STAX-12A automates the testing workflow following manual specimen preparation, sample addition, and loading of reagents and specified consumables. Testing is completed in approximately 1–2 hours, depending on the compatible assay and protocol.
Features
Integrated Automation and Workflow Efficiency
- Integrated automation: Following manual sample addition and loading, the system performs extraction, PCR reaction preparation, amplification, detection, and analysis to reduce hands-on steps.
- Rapid results: Completes multi-target nucleic acid testing in approximately 1–2 hours, depending on the assay and protocol.
- Flexible sample throughput: Processes 1–12 samples in parallel for urgent and routine testing needs.
- Precise liquid handling: Features 12 pipetting channels, liquid level detection, and a dispensing range of 5–50 μL. Larger volumes are handled through multiple dispensing operations.
- Compact footprint: A benchtop design integrates multiple testing functions for laboratories with limited space.
Multiplex Testing and Result Analysis
- Open reagent platform: Supports extraction and PCR reagents whose instructions for use specify compatibility with STAX-12A.
- Multiplex testing: Supports up to 8 fluorescence channels and up to 64 targets per sample, depending on the instrument configuration and compatible assay.
- User-friendly operation: Features a 10-inch touchscreen interface and barcode scanning for convenient operation.
- Real-time data visualization: Displays amplification curves in real time throughout the testing process.
- Assay-defined analysis: Provides amplification curves and Ct values, with qualitative or quantitative interpretation and applicable melting-curve analysis supported by compatible reagents and protocols.
Contamination Control and Laboratory Applications
- Contamination control: Combines film-covered consumables, automated tip handling, directed airflow, negative pressure, HEPA filtration, and UV disinfection to help reduce cross-contamination risk.
- Compatible applications: Supports automated molecular diagnostic workflows using extraction and PCR reagents whose instructions for use specify compatibility with STAX-12A, together with the consumables specified for the instrument.
Specifications
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Model
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STAX-12A
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Sample throughput
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1–12 samples per run
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Main functions
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Nucleic acid extraction, automated liquid dispensing, PCR amplification, multi-target fluorescence detection, and result analysis
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Pipetting channels
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12
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Pipetting volume range
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5–50 μL; larger volumes through multiple dispensing operations
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Extraction temperature control accuracy
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±5 °C
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Fluorescence channels
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Up to 8 channels
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Compatible fluorescent dyes
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FAM, SYBR Green, VIC, HEX, JOE, TET, ROX, Texas Red, Cy5, Quasar 705, Cy5.5, ATTO 425, Cy7, and AF405; depending on configuration
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Maximum targets per sample
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Up to 64, depending on the instrument configuration and compatible assay
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Run time
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Approximately 1–2 hours, depending on the assay and protocol
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Temperature change rate
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Heating: average ≥8 °C/s; maximum ≥10 °C/s. Cooling: average ≥5 °C/s; maximum ≥7 °C/s.
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User interface
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10-inch touchscreen with barcode scanning
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Air filtration
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Negative-pressure HEPA filtration system with directed internal airflow
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UV disinfection
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Chamber UV disinfection
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Dimensions
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720 × 350 × 660 mm
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Weight
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50 kg
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Operating temperature
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15–30 °C
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Operating humidity
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10–85% RH, non-condensing
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Power supply
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100–240 V AC, 50/60 Hz
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Rated power
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1,350 VA
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Reagent compatibility
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Open reagent platform; use reagents whose instructions specify STAX-12A compatibility
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Channel availability, target capacity, and test duration depend on the instrument configuration and compatible assay.
Applications
STAX-12A supports automated molecular diagnostic workflows using extraction and PCR reagents whose instructions for use specify compatibility with STAX-12A, together with the consumables specified for the instrument. BioPerfectus assay applications presented in the product leaflet include:
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Application
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Compatible Assay Panels
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Gastrointestinal infections
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Multiplex nucleic acid detection panels covering 28 or 32 gastrointestinal pathogen types.
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Respiratory infections
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Multiplex nucleic acid detection panels covering 12, 22, 23, 24, 25, 26, 27, or 28 respiratory pathogen types.
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Encephalitis and meningitis
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Multiplex nucleic acid detection panel covering 13 pathogen types associated with encephalitis and meningitis.
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Available panels, validated sample types, target combinations, and result interpretation criteria are defined by the applicable assay instructions for use.
Workflow
Prepare and manually add specimens → Load compatible reagents and specified consumables → Select protocols and confirm loading → Start the automated run → Review controls, curves, and results.
Certificate
IVDR in progress
